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Infectious Disease: Rubella
Vaccination: Measles Vaccine

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Total 595 results found since Jan 2013.

Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Semin Immunol. 2023 Sep 15;70:101842. doi: 10.1016/j.smim.2023.101842. Online ahead of print.ABSTRACTVaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, including smallpox, polio, measles, rubella, and, most recently, COVID-19. Yet, the effectiveness of vaccines varies among individuals. In fact, while some recipients mount a robust response to vaccination that protects them from the disease, others fail to respond. Multiple clinical and epidemiological factors contribute to this heterogeneity in responsiveness. Systems immunology studies fueled by advances in...
Source: Seminars in Immunology - September 17, 2023 Category: Allergy & Immunology Authors: Djamel Nehar-Belaid Mark Sokolowski Sathyabaarathi Ravichandran Jacques Banchereau Damien Chaussabel Duygu Ucar Source Type: research

Immunogenicity and safety of Mebella ™ vaccine developed by Human Biologicals Institute in a Phase II/III, randomized, multicentric, non-inferiority study
CONCLUSION: It was concluded from the study results that the test vaccine, Mebella™, was immunogenic and well tolerated and was non-inferior to the comparator vaccine, MR-VAC®, when administered to healthy subjects of 9 months to 49 years of age. Clinical Trial Registry of India Identifier: CTRI/2020/07/026930.PMID:37659893 | DOI:10.1016/j.vaccine.2023.08.065
Source: Vaccine - September 2, 2023 Category: Allergy & Immunology Authors: Sai Krishna Susarla Rahul Jahagirdar Kheya Ghosh Uttam S Srikanth Bhatt S Prashanth Vasudev Rajapantula M Satish B C Rajashakar G Sandhya L Rajendra Devi Prasad Sahoo Anand Kumar Kanakasapapathy Source Type: research

Real-world challenges in eligibility for MMR vaccination two years after autologous and allogeneic HSCT
Vaccine. 2023 Aug 29:S0264-410X(23)00778-8. doi: 10.1016/j.vaccine.2023.06.075. Online ahead of print.ABSTRACTMeasles outbreaks have raised concerns of fatal infections in immunocompromised patients. Canadian guidelines advise administration of live vaccines, such as measles, mumps, and rubella (MMR), two yearsafter hematopoietic stem cell transplant (HSCT) yet studies have not assessed eligibility based on medication contraindications. We retrospectively reviewed the charts of 72 autologous (auto-HSCT) and 68 allogeneic (allo-HSCT) recipients at the Windsor Regional Cancer Center to determine MMR reactivity and eligibilit...
Source: Vaccine - August 31, 2023 Category: Allergy & Immunology Authors: Gopika Punchhi Rainbow Negus Hammad Saif Sharon Pritchard Olivia Owen Aman Sehmbi Caroline Hamm Source Type: research

Timeliness of childhood vaccination in England: A population-based cohort study
We described vaccine uptake for representative antigens (pertussis, pneumococcus, measles) by age in days and stratified by ethnicity, region and birth cohort. Alluvial diagrams were used to illustrate common journeys through the vaccination schedule, and we applied survival analysis using accelerated failure time models (AFT) to predict age of vaccine receipt based on timing of previous doses.RESULTS: 573,015 children were followed up until their fifth birthday, when they had 90.16 % coverage for two doses of measles, mumps, rubella (MMR) vaccine and 88.78% coverage for four doses of diphtheria, tetanus, pertussis (DTP) v...
Source: Vaccine - August 13, 2023 Category: Allergy & Immunology Authors: Anne M Suffel Jemma L Walker Elizabeth Williamson Helen I McDonald Charlotte Warren-Gash Source Type: research

Direct and crowding-out effects of a Hepatitis B vaccination campaign
Econ Hum Biol. 2023 Jul 23;51:101279. doi: 10.1016/j.ehb.2023.101279. Online ahead of print.ABSTRACTWe evaluate the direct and spillover causal effects of a Hepatitis B (HB) vaccination campaign in French schools on the vaccination adherence of the targeted pupils. Using a regression discontinuity design, we show that this campaign created an exogenous shock on vaccination behavior, increasing the HB vaccination rate for children aged 11 and above. At the same time, we show a drop in the measles, mumps, and rubella (MMR) vaccination rate of the targeted pupils and an increase in the parental belief that measles is a benign...
Source: Economics and Human Biology - August 11, 2023 Category: Biology Authors: Cl émentine Garrouste Arthur Juet Anne-Laure Samson Source Type: research

Modeling the impact of vaccination for the immunization Agenda 2030: Deaths averted due to vaccination against 14 pathogens in 194 countries from 2021 to 2030
Vaccine. 2023 Aug 1:S0264-410X(23)00854-X. doi: 10.1016/j.vaccine.2023.07.033. Online ahead of print.ABSTRACTBACKGROUND: The Immunization Agenda 2030 (IA2030) Impact Goal 1.1. aims to reduce the number of future deaths averted through immunization in the next decade. To estimate the potential impact of the aspirational coverage targets for IA2030, we developed an analytical framework and estimated the number of deaths averted due to an ambitious vaccination coverage scenario from 2021 to 2030 in 194 countries.METHOD: A demographic model was used to determine annual age-specific mortality estimates associated with vaccine c...
Source: Vaccine - August 3, 2023 Category: Allergy & Immunology Authors: Austin Carter William Msemburi So Yoon Sim Katy A M Gaythorpe Philipp Lambach Ann Lindstrand Raymond Hutubessy Source Type: research

Long-term immunoprotection after live attenuated measles-mumps-rubella booster vaccination in children with juvenile idiopathic arthritis
CONCLUSION: The MMR booster vaccine demonstrated long-term immunogenicity in the majority of children with JIA from a large cohort, although lower percentages of protective measles antibody levels were observed in bDMARD users. Hence, it might be indicated to measure antibody levels at least five years after MMR booster vaccination in the latter group and advice an extra booster accordingly.PMID:37516575 | DOI:10.1016/j.vaccine.2023.07.052
Source: Vaccine - July 29, 2023 Category: Allergy & Immunology Authors: Mohamad Hamad Saied Joeri W van Straalen Sytze de Roock Gerrie C J de Joode-Smink Frans M Verduyn Lunel Joost F Swart Nico M Wulffraat Marc H A Jansen Source Type: research

Response to Vaccine-Derived Polioviruses Detected through Environmental Surveillance, Guatemala, 2019
Emerg Infect Dis. 2023 Aug;29(8):1524-1530. doi: 10.3201/eid2908.230236.ABSTRACTGuatemala implemented wastewater-based poliovirus surveillance in 2018, and three genetically unrelated vaccine-derived polioviruses (VDPVs) were detected in 2019. The Ministry of Health (MoH) response included event investigation through institutional and community retrospective case searches for acute flaccid paralysis (AFP) during 2018-2020 and a bivalent oral polio/measles, mumps, and rubella vaccination campaign in September 2019. This response was reviewed by an international expert team in July 2021. During the campaign, 93% of children ...
Source: Emerging Infectious Diseases - July 24, 2023 Category: Infectious Diseases Authors: Rodrigo Rodr íguez Elisa Ju árez Concepci ón F Estívariz Coralia Cajas Gloria Rey-Benito Mar ía Olga Bautista Amézquita Stacey Jeffries Miles Oscar Orantes Mar ía Cecilia Freire Ana-Elena Ch évez Leticia Castillo Signor Leanna Sayyad Claudia Jarqu Source Type: research